Percocet, a combination of oxycodone and acetaminophen, is commonly prescribed for pain after surgery or injury. But it’s also highly addictive. What begins as legitimate medical use can quickly turn into dependence. In 2022, over 2 million Americans were struggling with prescription opioid use disorder – a reminder of how many lives this crisis affects.
If you’re thinking about quitting Percocet, it’s normal to feel afraid of what withdrawal might bring. Understanding the timeline and symptoms—and knowing that you don’t have to go through it alone—can bring comfort and hope.
Why Does Percocet Withdrawal Happen?
Percocet affects the brain’s reward system, creating feelings of relaxation, pain relief, and sometimes even euphoria. Over time, your brain and body become so used to having the drug present that they can’t function normally without it.
When you stop taking Percocet, your nervous system goes into overdrive trying to restore balance. That’s what causes withdrawal symptoms. They’re not imaginary or signs of weakness—they’re a real physiological response to chemical changes in your brain and body.
People often describe Percocet withdrawal as a brutal combination of physical pain and emotional distress. It’s sometimes compared to a terrible flu—but with added anxiety, panic, and relentless cravings. For many, this is the reason attempts to quit alone are unsuccessful.
At Sequoia Recovery, we understand how intense withdrawal can feel. That’s why we offer medical detox services to help clients navigate this difficult stage safely and with as little discomfort as possible.
How Long Does Percocet Withdrawal Last?
So, how long does Percocet withdrawal last? The answer isn’t simple. It depends on how long someone has been taking Percocet, how high their daily dose was, and whether other substances are involved. Mental health, overall physical health, and even genetics play a role.
Still, most people follow a similar withdrawal timeline:
- 8–24 hours after the last dose: Early symptoms begin. You might feel restless, anxious, and achy. Sleep can become difficult. Some people start sweating or notice their heart racing.
- 2–4 days in: This is the hardest phase for many. Nausea, vomiting, diarrhea, severe muscle and bone pain, chills, and powerful cravings often peak during this window. People may also feel deeply depressed or panicked, convinced that symptoms will never end.
- 5–10 days: Physical symptoms gradually fade, but emotional symptoms linger. You might feel exhausted, moody, or have trouble concentrating. Appetite slowly returns, and sleep patterns start to normalize.
For some, the journey doesn’t end there. A smaller percentage of people—about 10–30%—experience post-acute withdrawal syndrome (PAWS), which can last weeks or months. PAWS can include anxiety, insomnia, irritability, and lingering cravings.
The Hidden Dangers of Detoxing Alone
Some people believe they can simply stop Percocet on their own, determined to “tough it out.” Detoxing alone carries serious risks.
Withdrawal can cause severe dehydration from vomiting and diarrhea, leading to electrolyte imbalances that affect heart function. Anxiety and depression can escalate into suicidal thoughts. Most concerning, intense cravings often drive people back to Percocet use. Tragically, after even a short break from opioids, a person’s tolerance drops. Returning to their previous dose can trigger a fatal overdose.
That’s why professional detox matters so deeply. At Sequoia Recovery, we provide round-the-clock medical care, medications that ease symptoms, and compassionate support from people who understand what you’re going through.
How to Prepare for Percocet Withdrawal
If you’re considering stopping Percocet, you deserve support and planning. The first step is talking to a medical professional who understands opioid withdrawal. Quitting cold turkey without guidance can be dangerous and usually makes symptoms worse.
A medical detox program can help you:
- Stay safe during withdrawal
- Receive medications to reduce symptoms and cravings
- Get emotional support during difficult moments
- Transition smoothly into longer-term treatment
Financial concerns often stop people from seeking help. It’s heartbreaking how many believe treatment is simply out of reach. Many people who need addiction treatment don’t get it because they thought they can’t afford it. At Sequoia Recovery, we work with many insurance plans and offer payment options. We’ll help you explore every resource available so cost doesn’t stand between you and recovery.
Why Long-Term Treatment Matters After Detox
Detox is an important first step—but it’s only the beginning. Without follow-up treatment, most people relapse because the mental and emotional drivers of addiction remain.
Imagine trying to stay sober while surrounded by old triggers, stress, or painful memories. Therapy, support groups, and relapse prevention strategies help people rebuild their lives. Studies show that 40% to 60% of people who engage in treatment maintain long-term recovery.
Let Sequoia Recovery Help You Take the First Step
If you’re asking, “How long does Percocet withdrawal last?”—the answer is: it varies. But one thing is certain: you shouldn’t go through it alone.
At Sequoia Recovery, we’ve helped countless people move from fear to freedom. We believe in compassionate, evidence-based care that treats not just addiction, but the person behind it. Whether you’re ready to start treatment today or just gathering information, we’re here to listen, guide, and help you reclaim your life.
Contact Sequoia Recovery if you’d like to talk about how to help someone safely begin recovery.
FAQs About How Long Percocet Withdrawal Lasts
Every person who comes to Sequoia Recovery has questions. Here’s what we hear most often—and what we want you to know.
How long does Percocet withdrawal last for most people?
For most, intense symptoms fade within 5 to 10 days, but emotional ups and downs can persist for weeks or months, especially if there’s underlying mental health issues. With professional help, symptoms are often milder and easier to manage.
Is Percocet withdrawal dangerous?
While not usually life-threatening in a direct medical sense, withdrawal can cause dehydration, blood pressure spikes, or mental health crises. The biggest risk is relapse—and overdose—after your tolerance drops. Supervised detox significantly reduces these risks.
What helps relieve Percocet withdrawal symptoms?
Medical detox can include medications like buprenorphine or clonidine to ease symptoms and cravings. Staying hydrated, eating small meals, and having emotional support are also crucial.
Will I definitely get PAWS after Percocet withdrawal?
Not everyone experiences PAWS, but about 10–30% of people recovering from opioids do. Symptoms include mood swings, insomnia, and lingering cravings. The good news is these symptoms gradually improve over time, especially with therapy and support.
How can I help someone going through Percocet withdrawal?
If someone you love is detoxing, offer support without judgment. Encourage them to seek professional care rather than going it alone. Simple things like preparing meals, offering rides, or helping with childcare can ease their burden. And remember to care for yourself, too—addiction affects the entire family.
